Ketamine may treat harmful drinking behavior by ‘rewriting drinking memories,’ researchers say
Researchers behind the ASPIRE trial want to take the drug even further. Their new goal is to have the drug approved to treat patients with major depressive disorder who have active suicidal ideation with intent.
“This is a specific vulnerable subset of patients with major depressive disorder and is especially meaningful as these patients are commonly excluded from clinical trials,”
“Ketamine was actually restoring many of the exact same synapses in their exact same configuration that existed before the animal was exposed to chronic stress,” he says.
In other words, the drug seemed to be repairing brain circuits that had been damaged by stress.
The FDA approved a new ketamine depression drug — here’s what’s next
An excellent piece by Dr. Sanjay Gupta outlining the benefits of ketamine infusions for depression.
A local news piece provides an overview of ketamine for depression